the research

March 13, 2025
Mist: Vaginal microbiome clinical study and effect of product usage
Sequential The Skin Microbiome Testing Co.™

To evaluate the vaginal microbiome in vivo (in human) in the presence of Curive Healthcare’s micellar cleansing mist:

1. A maintenance of the skin microbiome across individuals;

2. The general absence of significantly changing specific vaginal microbiome;

3. Characterising the vaginal microbiome using qPCR.

We designed unique probes targeting specific vaginal markers and conducted both absolute Absolute levels (Genome Copy/ul of DNA volume) and relative quantification to analyse the microbiome profile. This analysis was further correlated with the associated metadata.

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July 1, 2024
MIST: ASSESSMENT OF THE CUTANEOUS COMPATIBILITY AND ABSENCE OF ALLERGENIC POTENTIAL IN HUMANS AFTER REPEATED INSULT PATCH APPLICATIONS SUPERVISED BY THE DERMATOLOGIST
Zurko BioResearch
  • This study had as objective verifying the cutaneous compatibility and the absence of allergenic potential of a cosmetic product after repeated skin applications, under exaggerated experimental conditions.
  • The product was applied to the skin under patch 9 times during 3 consecutive weeks, across 55 participants of all skin types. After a minimum of two weeks of rest of the patch application, the product was reapplied under patch in duplicate sites.
  • The compatibility of the product with the skin was verified, after removing the patch, and through visual examination of the experimental area by the responsible technical expert and the dermatologist in charge of the study.
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July 23, 2024
Serum: CLINICAL EVALUATION OF THE SAFETY-IN-USE OF AN EXTERNAL VAGINAL MOISTURIZING SERUM ON THE EXTERNAL GENITALIA OF FEMALE VOLUNTEERS
RCTS, Inc., an ALS Global Company

The objective of this study was to evaluate the in-use safety of an external vaginal moisturizing serum on at least thirty (30) healthy, adult, female subjects between the ages of 35-65 years old. The study was conducted over a 2-week period using the following procedures:

  • External Gynecological Evaluations
  • Flora Evaluations
  • pH Assessments
  • Mid-Study Call-In
  • Self-Assessment Questionnaires for consumer perception
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May 20, 2024
Serum: Vaginal microbiome clinical study and effect of product usage
Sequential The Skin Microbiome Testing Co.™

The objective of this study was to evaluate the vaginal microbiome in vivo (in human) in the presence of an intimate serum:

  • A maintenance of the vaginal microbiome across individuals;
  • The general absence of significantly changing specific vaginal microbiome;
  • Characterising the vaginal microbiome using qPCR.

The intimate serum was used on a total of 33 participants over a 2-week period. Before the introduction of the new Serum, a three-day wash-out period was established, followed by serum application on a daily basis.

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March 01, 2024
Serum: ASSESSMENT OF THE CUTANEOUS COMPATIBILITY AND ABSENCE OF ALLERGENIC POTENTIAL IN HUMANS AFTER REPEATED INSULT PATCH APPLICATIONS SUPERVISED BY THE DERMATOLOGIST
Zurko BioResearch
  • This objective of this study was to verify the cutaneous compatibility and the absence of allergenic potential of a cosmetic product after repeated skin applications, under exaggerated experimental conditions.
  • A RIPT test is ‘repeated-insult patch test’ which is a two phase process that’s designed to evaluate the sensitization potential of a product.
  • The product was applied to the skin under patch 9 times during 3 consecutive weeks, across 50 participants of all skin types.
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